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kremen 2   Click here for help

GtoPdb Ligand ID: 3703

Synonyms: Dickkopf receptor 2 | Kremen protein 2 | Kringle domain-containing transmembrane protein 2 | Kringle-containing protein marking the eye and the nose
Compound class: Endogenous peptide in human, mouse or rat
Comment: Kremen 2 is an endogenous protein that interacts with Dickkopf (Dkk) family proteins and LRP5/6 to block Wnt/β-catenin signaling.
Species: Human
Peptide Sequence Click here for help
GSLHSPGLSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNPDGDVQPWCYVAET
EEGIYWRYCDIPSCHMPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRL
APATDCDQICFGHPGQLCGGDGRLGVYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWALGPPGAALELTFRLFEL
ADPRDRLELRDAASGSLLRAFDGARPPPSGPLRLGTAALLLTFRSDARGHAQGFALTYRGLQDAAEDPEAPEGSAQTPAA
PLDGANVSCSPRPGAPPAAIGARVFSTVTAVSVLLLLLLGLLRPLRRRSCLLAPGKGPPALGASRGPRRSWAVWYQQPRG
VALPCSPGDPQAEGSAAGYRPLSASSQSSLRSLISAL
Post-translational Modification
See Uniprot entry for a list of predicted post-translational modifications