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[D-Arg8]inotocin   Click here for help

GtoPdb Ligand ID: 14174

Compound class: Peptide
Comment: [D-Arg8]inotocin acts as a vasopressin V1a receptor antagonist [1]. Its sequence was derived from that of the insect oxytocin/vasopressin orthologue and neuropeptide inotocin.
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References
1. Di Giglio MG, Muttenthaler M, Harpsøe K, Liutkeviciute Z, Keov P, Eder T, Rattei T, Arrowsmith S, Wray S, Marek A et al.. (2017)
Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide.
Sci Rep, 7: 41002. [PMID:28145450]