mAb 3E3 [PMID: 22483115]

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Ligands
mAb 3E3 [PMID: 22483115]

GtoPdb Ligand ID: 14108

Compound class: Antibody

Comment: This antibody binds to the extracellular region of discoidin domain receptor 1 (DDR1) and inhibits its tyrosine kinase activity [1].

Summary
Biological activity
References

References
1. Carafoli F, Mayer MC, Shiraishi K, Pecheva MA, Chan LY, Nan R, Leitinger B, Hohenester E. (2012) Structure of the discoidin domain receptor 1 extracellular region bound to an inhibitory Fab fragment reveals features important for signaling. Structure, 20 (4): 688-97. [PMID:22483115]

References

1. Carafoli F, Mayer MC, Shiraishi K, Pecheva MA, Chan LY, Nan R, Leitinger B, Hohenester E. (2012)
Structure of the discoidin domain receptor 1 extracellular region bound to an inhibitory Fab fragment reveals features important for signaling.
Structure, 20 (4): 688-97. [PMID:22483115]