[3H]PSB-22219 [Ligand Id: 14166] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| P2Y12 receptor in Human [GtoPdb: 328] [UniProtKB: Q9H244] | ||||||||
| GtoPdb | Affinity for P12Y12 receptors on human platelets | - | 8.34 | pKd | 4.57 | nM | Kd | J Med Chem (2025) 68: 11279-11298 [PMID:40367388] |
| GtoPdb | Binding affinity for recombinant receptor in a radioligand membrane binding assay | - | 8.34 | pKd | 4.57 | nM | Kd | J Med Chem (2025) 68: 11279-11298 [PMID:40367388] |
| P2Y12 receptor in Mouse [GtoPdb: 328] [UniProtKB: Q9CPV9] | ||||||||
| GtoPdb | Binding affinity determined in mouse microglial cell preparations | - | 6.57 | pKd | 269 | nM | Kd | J Med Chem (2025) 68: 11279-11298 [PMID:40367388] |
| P2Y12 receptor in Rat [GtoPdb: 328] [UniProtKB: Q9EPX4] | ||||||||
| GtoPdb | Binding affinity determined in rat brain cortex preparations | - | 8.27 | pKd | 5.35 | nM | Kd | |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
