soficitinib [Ligand Id: 14068] activity data from GtoPdb

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  • Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
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  • tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
GtoPdb - - 8.92 pIC50 1.2 nM IC50 WO2020259584A1. Heterocyclic compounds for mediating tyrosine kinase 2 activity (2020)
tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
GtoPdb In a TYK2 kinase assay - 9.3 pIC50 0.5 nM IC50 WO2020259584A1. Heterocyclic compounds for mediating tyrosine kinase 2 activity (2020)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.